Many people believe that sexual orientation homosexuality vs. There are, however, a large number of studies indicating that prenatal factors...
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Although the homosexual and control groups showed a broad overlapping for all hormonal factors measured, highly significant differences between the groups were found without exception.
Minireview: Hormones and Human Sexual Orientation
- GENETIC MODIFICATIONS THAT RESPOND TO HORMONES IN THE WOMB MAY EXPLAIN THE DEVELOPMENT OF HOMOSEXUALITY.
- MEDICAL INTELLIGENCE FROM THE NEW ENGLAND JOURNAL OF MEDICINE — SERUM TESTOSTERONE LEVELS IN HOMOSEXUAL...
- THE LEVELS OF PLASMA TESTOSTERONE OF 19 YOUNG MALE HOMOSEXUALS (KINSEY GROUP VI) WERE FOUND TO BE SIGNIFICANTLY...
The hormonal theory of sexuality holds that, just as exposure to certain hormones plays a role in fetal sex differentiation , such exposure also influences the sexual orientation that emerges later in the adult. The hormonal theory of sexuality and gender identity holds that, just as exposure to certain hormones plays a role in fetal sex differentiation, such exposure also influences the sexual orientation and or gender identity that emerges later in the adult.
Differences in brain structure that come about from chemical messengers and genes interacting on developing brain cells are believed to be the basis of sex differences in countless behaviors, including sexual orientation. As seen in young children as well as in vervet and rhesus monkeys, sexually differentiated behavior in toy preference is differing in males versus females, where females prefer dolls and males prefer toy balls and cars; these preferences can be seen as early as 3—8 months in humans.
An endocrinology study by Garcia-Falgueras and Swaab postulated that "In humans, the main mechanism responsible of [ sic ] sexual identity and orientation involves a direct effect of testosterone on the developing brain. Sketching the argument briefly here, the authors say that sexual organs are differentiated first, and then the brain is sexually differentiated "under the influence, mainly, of sex hormones such as testosterone, estrogen and progesterone on the developing brain cells and under the presence of different genes as well The changes brought about in this stage are permanent.
Fetal gonads develop primarily based on the presence or absence of androgen hormones, mainly testosterone , dihydrotestosterone DHT and androstenedione ; production of testosterone and conversion into dihydrotestosterone during weeks 6 to 12 of pregnancy are key factors in the production of a male fetus's penis, scrotum and prostate.
Most extensively studied in organizational effects of hormones is congenital adrenal hyperplasia CAH. Girls with CAH are born with masculinized genitalia, which is corrected surgically as soon as possible. However, "CAH is not a perfect experiment", since, "social responses to masculinized genitalia or factors related to the disease itself" can confound results.
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If the same mechanisms control the development of INAH3 in humans, the smaller INAH3 of gay men could then be a marker of deficient exposure to androgens during ontogeny and even be a cause of the modified sexual orientation. These effects do not appear to be explained by differences in education or family background and may be the result of accumulation of antibodies in the mother during successive pregnancies against one or more proteins expressed specifically by the male brain.
No evidence of birth order effects have been observed in women. Second, clinical conditions associated with significant endocrine changes during embryonic life often result in an increased incidence of homosexuality. Recording the time spent with each partner and the type of behavior displayed toward them will provide a measure of a behavioral phenotype sexual partner preference that represents a reasonable although imperfect model of human sexual orientation.
Together with congenital adrenal hyperplasia, DES studies have provided little support of the prenatal hormone theory of sexual orientation; they do, however, provide the framework for possible pathways to a homosexual orientation for a small number of women.